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The critical importance of epigenetics in autoimmune-related skin diseases

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 43-57 doi: 10.1007/s11684-022-0980-8

Abstract: Autoimmune-related skin diseases are a group of disorders with diverse etiology and pathophysiology involvedGenetics and environmental factors may contribute to the development of these autoimmune disorders.this review, we discuss the most recent findings regarding the function of epigenetic mechanisms in autoimmune-relatedskin disorders, including systemic lupus erythematosus, bullous skin diseases, psoriasis, and systemic

Keywords： epigenetics     autoimmune-related skin diseases     DNA methylation     histone modifications     noncoding RNAs    

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Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 187-219 doi: 10.1007/s11684-015-0386-y

Abstract:

Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte-specificAlthough autoimmune hepatitis occurs in childhood, this review focuses on disease in adults.Since many features also occur in other chronic liver diseases, these scoring systems aid evaluationTransplant recipients are at risk for recurrent autoimmune hepatitis in the allograft, and de

Keywords： autoimmune hepatitis     autoantibodies     diagnosis     immunological diseases     drug-induced liver injury     therapy    

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Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 10-19 doi: 10.1007/s11684-015-0388-9

Abstract: inflammatory diseases.Here, we summarize recent research progress on Th17 function in the development and pathogenesis of autoimmunediseases.molecule compounds to manipulate Th17 function for potential therapeutic application to treat human autoimmunediseases, including rheumatoid arthritis, systemic lupus erythematosus, Sj?

Keywords： IL-17     Th17 cells     RORγt     autoimmune diseases     posttranslational modification     inhibitors    

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: distributional, and functional patterns and can rapidly respond to various insults and contribute to diverse diseasesγδ T cells play important roles in liver infection, non-alcoholic fatty liver disease, autoimmuneWe believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords： γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: Natural killer T cells play important roles in infections, tumors, autoimmune diseases, and metabolicdiseases.biology of natural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmuneliver diseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinomaindicate the dynamic alteration in the role of natural killer T cells during the progression of liver diseases

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholic    

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Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 534-548 doi: 10.1007/s11684-022-0953-y

Abstract: Autoimmune hepatitis (AIH) is a severe globally distributed liver disease that could occur at any age

Keywords： autoimmune hepatitis (AIH)     concanavalin A (Con A)     human menstrual blood-derived stem cells (MenSCs)    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 243-247 doi: 10.1007/s11684-012-0201-y

Abstract: Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes.Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

Keywords： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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Autoimmune regulator regulates autophagy in THP-1 human monocytes

Liang SHI, Li-Hua HU, Yi-Rong LI

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 336-341 doi: 10.1007/s11684-010-0096-4

Abstract: The autoimmune regulator (AIRE) is a crucial factor for the induction of central tolerance, and mutations

Keywords： autoimmune regulator     autophagy     monocytes     light chain 3 (LC3)    

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Laparoscopic treatment of liver diseases in children

Jia Wei, Jiexiong Feng

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 388-394 doi: 10.1007/s11684-011-0165-3

Abstract: Laparoscopic liver surgery has been increasingly used for the treatment of pediatric liver diseases overapplication of various laparoscopic instruments and the methods used for the laparoscopic treatment of liver diseases

Keywords： laparoscopic surgery     liver mass     pediatric    

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Prevalence of cardiovascular diseases in China

Jun-Jie XIAO MD, Yi-Han CHEN MD, PhD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 16-20 doi: 10.1007/s11684-010-0007-8

Abstract: Cardiovascular diseases (CVD) cause one third of all deaths in China, and the number is anticipated to

Keywords： cardiovascular diseases     prevalence     China     risk factors     prevention    

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Cultural differences define diagnosis and genomic medicine practice: implications for undiagnosed diseases

Xiaohong Duan, Thomas Markello, David Adams, Camilo Toro, Cynthia Tifft, William A. Gahl, Cornelius F. Boerkoel

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 389-394 doi: 10.1007/s11684-013-0281-3

Abstract: Specifically, we suggest that an undiagnosed diseases program in China will differ from the recentlyestablished Undiagnosed Diseases Program at the United States National Institutes of Health; a culturally

Keywords： genetics     cultural differences     undiagnosed diseases program    

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Diagnosis and therapy of lacrimal system diseases by micro lacrimal endoscope

Nan XIANG, Weikun HU, Jing YUAN, Guigang LI, Haixia LIU

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 113-117 doi: 10.1007/s11684-009-0001-1

Abstract: membranes, the characteristics of pathological changes and the predilection sites of lacrimal system diseasesThe lacrimal endoscope is a new method in the diagnosis of lacrimal system diseases.therapy under orthophoria, it will bring a great change to the diagnosis and therapy of lacrimal system diseases

Keywords： lacrimal apparatus diseases     endoscopes    

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Responses to emerging and re-emerging infectious diseases: One world, One health

Jianqing Xu, Jianguo Xu

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 1-2 doi: 10.1007/s11684-018-0619-y

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A Study on the Prevention and Control of Major Chronic Non-communicable Diseases Abroad

Zhang Zhuqin and Liu Depei

Strategic Study of CAE 2017, Volume 19, Issue 2,   Pages 112-116 doi: 10.15302/J-SSCAE-2017.02.019

Abstract:

Major chronic non-communicable diseases, including cardiovascular andcerebrovascular diseases, cancer, respiratory diseases, and diabetes, are prevalent in China and aroundIn order to effectively prevent and control chronic diseases, enhance national health, and promote economicThis project conducted a series of studies on the prevention and control of chronic diseases at homeBased on the project report, this paper describes the prevention and control of various chronic diseases

Keywords： chronic non-communicable diseases     cardiovascular and cerebrovascular diseases     cancer     respiratory diseases    

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Circulating microRNAs in cardiovascular diseases: from biomarkers to therapeutic targets

Feng Wang,Chen Chen,Daowen Wang

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 404-418 doi: 10.1007/s11684-014-0379-2

Abstract: crucial roles of some special miRNAs in heart development and pathophysiology of various cardiovascular diseasesThis has raised the possibility of using circulating miRNAs as biomarkers for diseases.In this review, we discuss the potential roles of circulating miRNAs in a variety of cardiovascular diseases

Keywords： microRNA     cardiovascular disease     biomarkers     therapeutic target    

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Title Author Date Type Operation

The critical importance of epigenetics in autoimmune-related skin diseases

Journal Article

Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Journal Article

Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article

Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Journal Article

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Journal Article

Autoimmune regulator regulates autophagy in THP-1 human monocytes

Liang SHI, Li-Hua HU, Yi-Rong LI

Journal Article

Laparoscopic treatment of liver diseases in children

Jia Wei, Jiexiong Feng

Journal Article

Prevalence of cardiovascular diseases in China

Jun-Jie XIAO MD, Yi-Han CHEN MD, PhD,

Journal Article

Cultural differences define diagnosis and genomic medicine practice: implications for undiagnosed diseases

Xiaohong Duan, Thomas Markello, David Adams, Camilo Toro, Cynthia Tifft, William A. Gahl, Cornelius F. Boerkoel

Journal Article

Diagnosis and therapy of lacrimal system diseases by micro lacrimal endoscope

Nan XIANG, Weikun HU, Jing YUAN, Guigang LI, Haixia LIU

Journal Article

Responses to emerging and re-emerging infectious diseases: One world, One health

Jianqing Xu, Jianguo Xu

Journal Article

A Study on the Prevention and Control of Major Chronic Non-communicable Diseases Abroad

Zhang Zhuqin and Liu Depei

Journal Article

Circulating microRNAs in cardiovascular diseases: from biomarkers to therapeutic targets

Feng Wang,Chen Chen,Daowen Wang

Journal Article